全文下载: 链接: https://pan.baidu.com/s/1gdMPShpxRa-dFIA5npS1SQ 提取码: 6xgw 212. Ming H, Li B, Tian H, Qin S, Zhang T, Liu S, Gao Y, Yang C, Chen L, Ni J, Nice EC, Jia Y, Huang C, Jing J. Copper-Coordinated Self-assembly Nanogels for Efficient Cancer Immunotherapy by Synergistic Suppression of Tumor-infiltrating Regulatory T cells. Chem Eng J. 2024; 500:157288. 211. Yan H, Cheng W, Qin S, Zuo J, Li L, Zhang J, Chang Q, Yan Y, Wang S, Huang C, Zhang H. Bioengineering human heavy-chain nanoferritin for glioblastoma multiforme-specific delivery and efficient immunotherapy. Chem Eng J. 2024; 157581. 210. Peng 209. Yang C, Ming H, Li B, Liu S, Chen L, Zhang T, Gao Y, He T, Huang C, Du Z. A pH and glutathione-responsive carbon monoxide-driven nano-herb delivery system for enhanced immunotherapy in colorectal cancer. J Control Release. 2024; 376:659-677. 208. Zuo 207. Ni J, Tian H, Qin S, Zhang T, Nice EC, Huang C, Wang H, Disulfide bond-rich Nano-Silica for High-Efficiency cancer immunotherapy using synergistic endoplasmic reticulum stress cooperated mitochondrial dysfunction. Chem Eng J. 2024,154877. 206. Chen L, Ming H, Li B, Yang C, Liu S, Gao Y, Zhang T, Huang C, Lang T, Yang Z. Tumor-Specific Nano-Herb Delivery System with High L-Arginine Loading for Synergistic Chemo and Gas Therapy against Cervical Cancer. Small. 2024; 5:e2403869. 205. Zhang X, Tian H, Chen Y, Liang B, Nice EC, Huang C, Xie N, Zheng S. A metal-organic nanoframework for efficient colorectal cancer immunotherapy by the cGAS-STING pathway activation and immune checkpoint blockade. J Nanobiotechnol. 2024; 22:592 204. Duan J, Huang Z, Qin S, Li B, Zhang Z, Liu R, Wang K, Nice EC, Jiang J, Huang C. Oxidative stress induces extracellular vesicle release by upregulation of HEXB to facilitate tumour growth in experimental hepatocellular carcinoma. J Extracell Vesicles. 2024; 13(7):e12468. 203. Wu H, Li B, Shao J, Kong Q. Tumor-oriented and chemo-photothermal nanoplatform capable of sensitizing chemotherapy and ferroptosis against osteosarcoma metastasis. Int J Biol Macromol. 2024; 269(Pt 2):132019. 202. Gao Y, Tian H, Zhang T, Deng K, Liu S, Li J, Nice EC, Huang C, Ding H, Xuan R. Step-by-step Guided Photo-chemotherapy Nanoplatforms for Efficiently Suppressing Cervical Carcinoma Metastasis by Hijacking Intracellular Metabolism. Chem Eng J. 2024; 151754. 201. Deng K, Tian H, Zhang T, Gao Y, Nice EC, Huang C, Xie N, Ye G, Zhou Y. Chemo-photothermal nanoplatform with diselenide as the key for ferroptosis in colorectal cancer. J Control Release. 2024; 366:684-693. (ESI高被引论文) 200. Liu S, Tian H, Ming H, Zhang T, Gao Y, Liu R, Chen L, Yang C, Nice EC, Huang C, Bao J, Gao W, Shi Z. Mitochondrial-Targeted CS@KET/P780 Nanoplatform for Site-Specific Delivery and High-Efficiency Cancer Immunotherapy in Hepatocellular Carcinoma. Adv Sci (Weinh). 2024:e2308027. 199. Ding K, Tian H, Li L, Liu S, Ding N, Nice EC, Bao J, Gao W, Shi Z. Drug Repurposing-based Nanoplatform Via Modulating Autophagy to Enhance Chemo-phototherapy Against Colorectal Cancer. J Nanobiotechnol. 2024; 22(1):202. 198. He B, Huang Z, Qin S, Peng P, Duan X, Wang L, Ye Q, Wang K, Jiang J, Li B, Liu R, Huang C. Enhanced SLC35B2/SAV1 sulfation axis promotes tumor growth through inhibiting Hippo signaling in hepatocellular carcinoma. Hepatology. 2024; 10.1097 197. Huang Z, Zhou L, Duan J, Qin S, Jiang J, Chen H, Wang K, Liu R, Yuan M, Tang X, Nice EC, Wei Y, Zhang W*, Huang C*. Oxidative Stress Promotes Liver Cancer Metastasis via RNF25-Mediated E-Cadherin Protein Degradation. Adv Sci. 2024; 29:e2306929. 196. Zhang T, Tian H, Qin S, Gao Y, Zhang X, Nice EC, Du Z, Huang C. Nanoengineering Calcium Peroxide-based Site-specific Delivery Platform to Efficiently Activate the cGAS-STING Pathway for Cancer Immunotherapy by Amplified Endoplasmic Reticulum Stress. Adv Funct Mater. 2024; 2313384. 195.Lu S, Tian H, Li B, Li L, Jiang H, Gao Y, Zheng L, Huang C, Zhou Y, Du Z, Xu J. An Ellagic Acid Coordinated Copper-Based Nanoplatform for Efficiently Overcoming Cancer Chemoresistance by Cuproptosis and Synergistic Inhibition of Cancer Cell Stemness. Small. 2023; 3:e2309215. 194. Cao J, Zhang Z, Zhou L, Luo M, Li L, Li B, Nice EC, He W, Zheng S, Huang C. Oncofetal reprogramming in tumor development and progression: novel insights into cancer therapy. MedComm. 2023; 4(6):e427 193. Li B, Ming H, Qin S, Zhou L, Huang Z, Jin P, Peng L, Luo M, Zhang T, Wang K, Liu R, Liou YC, Nice EC, Jiang J, Huang C. HSPA8 activates Wnt/β-catenin signaling to facilitate BRAF V600E colorectal cancer progression by CMA-mediated CAV1 degradation. Adv Sci. 2023; 16:e2306535 192. Liu G, Li B, Qin S, Nice EC, Yang J, Yang L, Huang C. Redox signaling-mediated tumor extracellular matrix remodeling: pleiotropic regulatory mechanisms. Cell Oncol (Dordr). 2023. 47(2):429-445. 191. Tan Y, Wang Z, Xu M, Li B, Huang Z, Qin S, Nice EC, Tang J, Huang C. Oral squamous cell carcinomas: state of the field and emerging directions. Int J Oral Sci. 2023; 15(1):44. (ESI高被引论文) 190. Wang K, Fu S, Dong L, Zhang D, Wang M, Wu X, Shen E, Luo L, Li C, Nice EC, Huang C, Zou B. Periplocin suppresses the growth of colorectal cancer cells by triggering LGALS3 (galectin 3)-mediated lysophagy. Autophagy. 2023; 1-19. 189. Jiang H, Tian H, Wang Z, Li B, Chen R, Luo K, Lu S, Nice EC, Zhang W, Huang C, Zhou Y, Zheng S, Gao F. Laser-activatable oxygen self-supplying nanoplatform for efficiently overcoming colorectal cancer resistance by enhanced ferroptosis and alleviated hypoxic microenvironment. Biomater Res. 2023; 27(1):92. 188. Tian H, Duan J, Qin S, Li B, Edouard C. Nice, Zhang W, Lang T, Zhang H, Huang C. Clinical Chemotherapeutic Agent Coordinated Copper-based Nanoadjuvants for Efficiently Sensitizing Cancer Chemo-immunotherapy by Cuproptosis-mediated Mitochondrial Metabolic Reprogramming. Adv Funct Mater. 2023, 2306584. 187. Liu R, Li Q, Qin S, Qiao L, Yang M, Liu S, Nice EC, Zhang W, Huang C, Zheng S, Gao W. Sertaconazole-repurposed nanoplatform enhances lung cancer therapy via CD44-targeted drug delivery. J Exp Clin Cancer Res. 2023; 42(1):188. 186. Liang J, Li L, Tian H, Wang Z, Liu G, Duan X, Guo M, Liu J, Zhang W, Nice EC, Huang C, He W, Zhang H, Li Q. Drug Repurposing-Based Brain-Targeting Self-Assembly Nanoplatform Using Enhanced Ferroptosis against Glioblastoma. Small. 2023:e2303073. 185. Huang Z, Tan Y, Zhang W, Tang X, Nice EC*, Huang C*. Hippo signaling in cancer: regulatory mechanisms and therapeutic strategies. Aust J Chem. 2023; 76(6-8),399-412. 184. Jia W, Huang Z, Zhou L, Liou YC, Di Virgilio F, Ulrich H, Illes P, Zhang W, Huang C, Tang Y. Purinergic signalling in cancer therapeutic resistance: From mechanisms to targeting strategies. Drug Resist Updat. 2023; 70:100988. 183. Duan X, Tian H, Zheng S, Zhu J, Li C, He B, Li L, Jiang H, Lu S, Feng Y, T. Bentley G, Zhang W, Huang C, Gao W, Xie N , Xie K. Photothermal-starvation Therapy Nanomodulator Capable of Inhibiting Colorectal Cancer Recurrence and Metastasis by Energy Metabolism Reduction. Adv Healthc Mater. 2023; 12(26):e2300968. 182. Jin P, Li L, Nice EC, Huang C. Nanomedicine based modulation of redox status for cancer therapy. Aust J Chem. 2023; 76(6-8),337-350. 181. Jiang H, Zuo J, Li B, Chen R, Luo K, Xiang X, Lu S, Huang C, Liu L*, Tang J*, Gao F*. Drug-induced Oxidative Stress in Cancer Treatments: Angel or Devil? Redox Biol. 2023; 63:102754.(ESI高被引论文) 180. Li Q, Zhou L, Qin S, Huang Z, Li B, Liu R, Yang M, Nice EC, Zhu H*, Huang C*. Proteolysis-targeting chimeras in biotherapeutics: current trends and future applications. Eur J Med Chem. 2023; 115447. 179. Ding N, He K, Tian H, Li L, Li Q, Lu S, Ding K, Liu J, Nice EC, Zhang W, Huang C*, Tang Y*, Shen Z*. Carrier-free delivery of thymopentin-regulated injectable nanogels via an enhanced cancer immunity cycle against melanoma metastasis. Materials Today Bio. 2023; 20:100645. 178. Li L, Peng P, Ding N, Jia W, Huang C*, Tang Y*. Oxidative Stress, Inflammation, Gut Dysbiosis: What Can Polyphenols Do in Inflammatory Bowel Disease. Antioxidants (Basel). 2023; 12(4):967. (ESI高被引论文) 177. Zhang X, Wang L, Li B, Shi J, Xu J, Yuan M. Targeting Mitochondrial Dysfunction in Neurodegenerative Diseases: Expanding the Therapeutic Approaches by Plant-Derived Natural Products. Pharmaceuticals (Basel). 2023; 16(2):277. 176. Wang K, Luo L, Fu S, Wang M, Wang Z, Dong L, Wu X, Dai L, Peng Y, Shen G, Chen H, Nice EC, Wei X, Huang C. PHGDH Arginine Methylation by PRMT1 Promotes Serine Synthesis and Represents a Therapeutic Vulnerability in Hepatocellular Carcinoma. Nat Commun. 2023; 14(1):1011. 175. Qiao L, Qin S, Weng N, Li B, Luo M, Zhang Z, Zhou L, Wang D, Huang C. Discovery of Canine Drug Toceranib Phosphate as a Repurposed Agent Against Human Hepatocellular Carcinoma. Liver Int. 2023;43(4):928-944. 174. Li Q, Qin S, Tian H, Liu R, Qiao L, Liu S, Li B, Yang M, Shi J, Nice EC, Li J, Lang T, Huang C. Nano-Econazole Enhanced PD-L1 Checkpoint Blockade for Synergistic Anti-Tumor Immunotherapy Against Pancreatic Ductal Adenocarcinoma. Small. 2023;e2207201. 173. Ming H, Li B, Jiang J, Qin S, Nice EC, He W, Lang T, Huang C. Protein degradation: expanding the toolbox to restrain cancer drug resistance. J Hematol Oncol. 2023;16(1):6. 172. Jia W, Zhou L, Li L, Zhou P, Shen Z. Nano- Based Drug Delivery of Polyphenolic Compounds for Cancer Treatment: Progress, Opportunities, and Challenges. Pharmaceuticals (Basel). 2023;16(1):101. 171. Tian H, Cao J, Li B, Nice EC, Mao H, Zhang Y, Huang C*. Managing the immune microenvironment of osteosarcoma: the horizons for osteosarcoma treatment. Bone research. 2023;11(1):11. (ESI高被引论文) 170. Li L, Tian H, Zhang Z, Ding N, He K, Lu S, Liu R, Wu P, Wang Y, He B, Luo M, Peng P, Yang M, Nice EC, Huang C, Xie N*, Wang D*, Gao W*. Carrier-Free Nanoplatform via Evoking Pyroptosis and Immune Response against Breast Cancer. ACS Appl Mater Interfaces. 2023;15(1):452-468. 169. Xie N, Shen G, Gao W, Huang Z, Huang C, Fu L*. Neoantigens: promising targets for cancer therapy. Signal Transduct Target Ther. 2023;8(1):9.(ESI高被引论文) 168. Qin S, Zhang Z, Huang Z, Luo Y, Weng N, Li B, Tang Y, Zhou L, Jiang J, Lu Y, Shao J, Xie N, Nice EC, Chen Z, Zhang J, Huang C*. CCT251545 Enhances Drug Delivery and Potentiates Chemotherapy in Multidrug-Resistant Cancers by Rac1-Mediated Macropinocytosis. Drug Resistance Updates. 2023; 66:100906. 167. Wang S, Zhou L, Tian H, Li B, Su M, Li Q, Nice EC, Huang C, Shao J, He T. Site-specific nanomodulator capable of modulation apoptosis for enhanced colorectal cancer chemo-photothermal therapy. J Nanobiotechnology. 2023;21(1):24. 166. Jiang J, Chen H, Jin P, Zhou L, Peng L, Huang Z, Qin S, Li B, Ming H, Luo M, Xie N, Gao W, Nice EC, Yu Q, Wei Y, Huang C*. Targeting PSAT1 to mitigate metastasis in tumors with p53-72pro variant. Signal Transduct Target Ther. 2023;8(1):65. 165. Li L, Jin P, Guan Y, Luo M, Wang Y, He B, Li B, He K, Cao J, Huang C, Li J, Shen Z. Exploiting Polyphenol Mediated Redox Reorientation in Cancer Therapy. Pharmaceuticals (Basel). 2022 Dec 12;15(12):1540. 164. Shi J, Tian H, Peng L, Huang C, Nice EC, Zou B, Zhang H*. A nanoplatform reshaping intracellular osmolarity and redox homeostasis against colorectal cancer.J Control Release. 2022;352:766-775. 163. Jia W, Tian H, Jiang J, Zhou L, Li L, Luo M, Ding N, Nice EC, Huang C*, Zhang H*. Brain-Targeted HFn-Cu-REGO Nanoplatform for Site-Specific Delivery and Manipulation of Autophagy and Cuproptosis in Glioblastoma. Small. 2022;e2205354. 162. Jin P, Jiang J, Zhou L, Huang Z, Qin S, Chen HN, Peng L, Zhang Z, Li B, Luo M, Zhang T, Ming H, Ding N, Li L, Xie N, Gao W, Zhang W, Nice EC, Wei Y, Huang C*. Disrupting metformin adaptation of liver cancer cells by targeting the TOMM34/ATP5B axis. EMBO Mol Med. 2022:e16082. 161. Lu S, Tian H, Li L, Li B, Yang M, Zhou L, Jiang H, Li Q, Wang W, Nice EC, Xie N*, Huang C*, Liu L*. Nanoengineering A Zeolitic Imidazolate Framework-8 Capable of Manipulating Energy Metabolism Against Cancer Chemo-Phototherapy Resistance. Small. 2022:e2204926. 160. Zhou L, Jiang J, Huang Z, Jin P, Peng L, Luo M, Zhang Z, Chen Y, Xie N, Gao W, Nice EC, Li J*, Chen H*, Huang C*. Hypoxia-induced lncRNA STEAP3-AS1 activates Wnt/β-catenin signaling to promote colorectal cancer progression by preventing m6A-mediated degradation of STEAP3 mRNA. Mol Cancer. 2022;21(1):168.
159. Duan J, Huang Z, Nice EC, Xie N*, Chen M*, Huang C*. Current advancements and future perspectives of long noncoding RNAs in lipid metabolism and signaling. J Adv Res. 2022:S2090-1232(22)00188-6.
158. Tian H, Zhang T, Qin S ,Huang Z, Zhou L, Shi J, Nice EC, Xie N, Huang C*, Shen Z* . Enhancing the therapeutic efficacy of nanoparticles for cancer treatment using versatile targeted strategies. J Hematol Oncol. 2022;15(1):132.(ESI高被引论文) 157. Jin P, Jiang J, Zhou L, Huang Z, Nice EC, Huang C*, Fu L*. Mitochondrial adaptation in cancer drug resistance: prevalence, mechanisms, and management. J Hematol Oncol. 2022;15,97.(ESI高被引论文) 156. Tian H, Zhou L, Wang Y, Nice EC, Huang C*, Zhang H*. A targeted nanomodulator capable of manipulating tumor microenvironment against metastasis. J Control Release. 2022;348:590-600. (ESI高被引论文) 155. Qin S, Li B, Ming H, Nice EC, Zou B*, Huang C*. Harnessing redox signaling to overcome therapeutic-resistant cancer dormancy. Biochim Biophys Acta Rev Cancer. 2022;1877(4):188749. 154. Luo M, Zhou L, Huang Z, Li B, Nice EC, Xu J*, Huang C*. Antioxidant therapy in cancer: rationale and progress. Antioxidants. 2022;11(6):1128. (ESI高被引论文) 153. Huang Z, Zhang Z, Zhou C*, Liu L*, Huang C*. Epithelial-mesenchymal transition: The history, regulatory mechanism, and cancer therapeutic opportunities. MedComm. 2022;3(2):e144. 152. Ming H, Li B, Tian H, Zhou L, Jiang J, Zhang T, Qiao L, Wu P, Nice EC, Zhang W, He W*, Huang C*, Zhang H*. A minimalist and robust chemo-photothermal nanoplatform capable of augmenting autophagy-modulated immune response against breast cancer. Mater Today Bio. 2022;15:100289. 151. Shi J, Zhou L, Huang H, Peng L, Xie N, Nice EC, Fu L, Jiang C*, Huang C*. Repurposing oxiconazole against colorectal cancer via PRDX2-mediated autophagy arrest. Int J Biol Sci. 2022;18(9):3747-61. 150. Fan Q, Zuo J, Tian H, Huang C, Nice EC, Shi Z*, Kong Q*. Nanoengineering a metal-organic framework for osteosarcoma chemo-immunotherapy by modulating indoleamine-2,3-dioxygenase and myeloid-derived suppressor cells. J Exp Clin Canc Res. 2022;41(1):1-17. 149. He B, Huang Z, Huang C*, Nice EC*. Clinical applications of plasma proteomics and peptidomics: towards precision medicine. Proteomics Clin Appl. 2022;2100097.
148. Liu R, Peng L, Zhou L, Huang Z, Zhou C*, Huang C*. Oxidative stress in cancer immunotherapy: molecular mechanisms and potential applications. Antioxidants (Basel). 2022;11(5):853.
147. Wang Y, Huang Z, Li B, Liu L*, Huang C*. The emerging roles and therapeutic implications of epigenetic modifications in ovarian cancer. Front Endocrinol. 2022;766. 146. Peng L, Jiang J, Zhou L, Nice EC, Huang C*. A cellular thermal shift assay for detecting amino acid sites involved in drug target engagement. STAR Protoc. 2022;101423. 145. Zuo J, Zhang Z, Luo M, Zhou L, Nice EC, Zhang W, Wang C*, Huang C*. Redox signaling at the crossroads of human health and disease. MedComm. 2022;3(2):e127. 143. Zuo J, Zhang Z, Li M, Yang Y, Zheng B, Wang P*, Huang C*, Zhou S*. The crosstalk between reactive oxygen species and noncoding RNAs: from cancer code to drug role. Mol Cancer. 2022;21(1):30. 142. Weng N, Qin S, Liu J, Huang X, Jiang J, Zhou L, Zhang Z, Xie N, Wang K, Jin P, Luo M, Peng L, Nice EC, Goel A, Han S*, Huang C*, Zhu Q*. Repurposing econazole as a pharmacological autophagy inhibitor to treat pancreatic ductal adenocarcinoma. Acta Pharm Sin B. 2022;12(7):3085-3102. 141. Luo M, Huang Z, Yang X, Chen Y, Jiang J, Zhang L, Zhou L, Qin S, Jin P, Fu S, Peng L, Li B, Fang Y, Pu W, Gong Y, Liu Y, Ren Z, Liu QL, Wang C, Xiao F, He D, Zhang H, Li C, Xu H, Dai L, Peng Y, Zhou ZG, Huang C*, Chen HN*. PHLDB2 mediates cetuximab resistance via interacting with EGFR in latent metastasis of colorectal cancer. Cell Mol Gastroenterol Hepatol. 2021;S2352-345X(21):00261-7. 140. Zhang Z, Qin S, Chen Y, Zhou L, Yang M, Tang Y, Zuo J, Zhang J, Mizokami A, Nice EC, Chen H*, Huang C*, Wei X*. Inhibition of NPC1L1 disrupts adaptive responses of drug-tolerant persister cells to chemotherapy. EMBO Mol Med. 2022;14(2):e14903. (ESI高被引论文) 139. Yang M, Zhang Z, Nice EC, Wang C*, Zhang W*, Huang C*. Psychological intervention to treat distress: An emerging frontier in cancer prevention and therapy. Biochim Biophys Acta Rev Cancer. 2021;1877(1):188665.(被WHO收录) 138. Peng L, Jiang J, Chen H, Zhou L, Huang Z, Qin S, Jin P, Luo M, Li B, Shi J, Xie N, Deng L, Liou Y, Nice EC, Huang C*, Wei Y. Redox-sensitive cyclophilin A elicits chemoresistance through realigning cellular oxidative status in colorectal cancer. Cell Rep. 2021;37(9):110069. 137. Wang Z, Guo K, Liu Y, Huang C*, Wu M*. Dynamic impact of virome on colitis and colorectal cancer: immunity, inflammation, prevention and treatment. Semin Cancer Biol. 2021;S1044-579X(21):00254-6. 136. Li B, Huang Y, Ming H, Nice EC, Xuan R*, Huang C*. Redox Control of the Dormant Cancer Cell Life Cycle. Cells. 2021;10(10):2707. 135. Zheng X, Liu R, Zhou C, Yu H, Luo W, Zhu J, Liu J, Zhang Z, Xie N, Peng X, Xu X, Cheng L, Yuan Q, Huang C*, Zhou X*. ANGPTL4-mediated promotion of glycolysis facilitates the colonization of Fusobacterium nucleatum in colorectal cancer. Cancer Res. 2021;81(24):6157-6170. 134. Jiang J, Li B, He W*, Huang C*. Dietary serine supplementation: Friend or foe? Curr Opin Pharmacol. 2021;61:12-20. 133. Peng L, Yin HY*, Huang C*. CNMa-CNMa receptor at microbiome-gut-brain axis: novel target to regulate feeding decision. Signal Transduct Target Ther. 2021;6(1):283. 132. Tian H, Zhao S, Nice EC, Huang C, He W*, Zou B*, Lin J*. A cascaded copper-based nanocatalyst by modulating glutathione and cyclooxygenase-2 for hepatocellular carcinoma therapy. J Colloid Interface Sci. 2021;607(2):1516-1526. 131. An Y, Jiang J, Zhou L, Shi J, Jin P, Li L, Peng L, He S, Zhang W, Huang C, Zou B*, Xie N*. Peroxiredoxin 1 is essential for natamycin-triggered apoptosis and protective autophagy in hepatocellular carcinoma. Cancer Lett. 2021;521:210-223. 130. Gao W, Huang Z, Duan J, Nice EC, Lin J*, Huang C*. Elesclomol induces copper-dependent ferroptosis in colorectal cancer cells via degradation of ATP7A. Mol Oncol. 2021;15(12):3527-44. 129. Luo M, Yang X, Chen HN, Nice EC*, Huang C*. Drug resistance in colorectal cancer: An epigenetic overview. Biochim Biophys Acta Rev Cancer. 2021;1876(2):188623. 128. Zhang Z, Shi J, Nice EC, Huang C*, Shi Z*. The Multifaceted Role of Flavonoids in Cancer Therapy: Leveraging Autophagy with a Double-Edged Sword. Antioxidants (Basel). 2021;10(7):1138. 127. Su M, Zhang Z, Zhou L, Han C, Huang C*, Nice EC*. Proteomics, Personalized Medicine and Cancer. Cancers (Basel). 2021;13(11):2512. 126. Zhang P, Zou B, Liou YC*, Huang C*. The pathogenesis and diagnosis of sepsis post burn injury. Burns Trauma. 2021;9:047. 125. Wang Z, Guo K, Gao P, Pu Q, Lin P, Qin S, Xie N, Hur J, Li C*, Huang C*, Wu M*. Microbial and genetic-based framework identifies drug targets in inflammatory bowel disease. Theranostics. 2021;11(15):7491-506. 124. Wang Z, Pu Q*, Huang C*, Wu M*. Crosstalk Between Lung and Extrapulmonary Organs in Infection and Inflammation. Adv Exp Med Biol. 2021;1303:333-50. 123. Huang Z, Xie N, Illes P, Di Virgilio F, Ulrich H, Semyanov A, Verkhratsky A, Sperlagh B, Yu S, Huang C*, Tang Y*. From purines to purinergic signalling: molecular functions and human diseases. Signal Transduct Target Ther. 2021; 6(1):162. (ESI 高被引论文) 122. Liu J, Huang Z, Chen HN, Qin S, Chen Y, Jiang J, Zhang Z, Luo M, Ye Q, Xie N, Zhou Z, Wei Y, Xie K*, Huang C*. ZNF37A promotes tumor metastasis through transcriptional control of THSD4/TGF-β axis in colorectal cancer. Oncogene. 2021; 40(19):3394-407. 121. Ming H, Li B, Zhou L, Goel A*, Huang C*. Long non-coding RNAs and cancer metastasis: Molecular basis and therapeutic implications. Biochim Biophys Acta Rev Cancer. 2021; 1875(2):188519. 120. Xie N, Zhang L, Gao W, Huang C, Huber PE, Zhou X, Li C*, Shen G*, Zou B*. NAD + metabolism: pathophysiologic mechanisms and therapeutic potential. Signal Transduct Target Ther. 2020; 5(1):227.(ESI 高被引论文) 119. Qin S, Jiang J, Lu Y, Nice EC, Huang C*, Zhang J*, He W*. Emerging role of tumor cell plasticity in modifying therapeutic response. Signal Transduct Target Ther. 2020; 5(1):228. 118. Zhou L, Zhang Z, Huang Z, Nice EC, Zou B*, Huang C*. Revisiting cancer hallmarks: insights from the interplay between oxidative stress and non-coding RNAs. Molecular Biomedicine. 2020. doi.org/10.1186/s43556-020-00004-1. 117. Peng L, Jiang J, Tang B, Nice EC, Zhang YY*, Xie N*. Managing therapeutic resistance in breast cancer: from the lncRNAs perspective. Theranostics. 2020; 10(23):10360-77. 116. Li B, Jiang J, Assaraf YG, Xiao H, Chen Z-S*, Huang C*. Surmounting Cancer Drug Resistance: New Insights from the perspective of N6-Methyladenosine RNA Modification. Drug Resist Updat. 2020; 53:100720.(ESI 高被引论文) 115. Jiang J, Peng L, Wang K*, Huang C*. Moonlighting Metabolic Enzymes in Cancer: New Perspectives on the Redox Code. Antioxid Redox Signal. 2020; 34(13):979-1003. 114. Zhang Z, Zhou L, Xie N, Nice EC, Zhang T*, Cui Y-P*, Huang C*. Overcoming cancer therapeutic bottleneck by drug repurposing. Signal Transduct Target Ther. 2020; 5(1):113.(ESI 高被引论文) 113. Zhang P, Li T, Wu X, Nice EC, Huang C*, Zhang Y*. Oxidative stress and diabetes: antioxidative strategies. Front Med. 2020; 14(5):583-600. (ESI 高被引论文) 112. Huang Z, Zhou J-K, Peng Y, He W*, Huang C*. The role of long noncoding RNAs in hepatocellular carcinoma. Mol Cancer. 2020; 19(1):77. (ESI 高被引论文) 111. Huang Z, Zhou J-K, Wang K, Chen H-N, Qin S, Liu J, Luo M, Chen Y, Jiang J, Zhou L, Zhu L, He J, Li J, Pu W, Gong Y, Li J, Ye Q, Dong D, Hu H, Zhou Z, Dai L, Wei Y, Huang C*, Wei X*, Peng Y*. PDLIM1 inhibits tumor metastasis through activating Hippo signaling in hepatocellular carcinoma. Hepatology. 2020; 71(5):1643-59. 110. Zhang Z, Gao W, Zhou L, Chen Y, Qin S, Zhang L, Liu J, He Y, Lei Y, Chen H-N, Han J, Zhou Z-G, Nice EC, Li C, Huang C*, Wei X*. Repurposing Brigatinib for the Treatment of Colorectal Cancer Based on Inhibition of ER-phagy. Theranostics. 2019; 9(17):4878-92. 109. He Y, Mohamedali A, Huang C, Baker MS*, Nice EC*. Oncoproteomics: Current status and future opportunities. Clin Chim Acta. 2019; 495:611-24. 108. An Y, Zhou L, Huang Z, Nice EC, Zhang H*, Huang C*. Molecular insights into cancer drug resistance from a proteomics perspective. Expert Rev Proteomics. 2019; 16(5):413-29. 107. Jiang J, Zhang L, Chen H-N, Lei Y, Zhang T, Wang Y, Jin P, Lan J, Zhou L, Huang Z, Li B, Liu Y, Gao W, Xie K, Zhou L, Nice EC, Peng Y, Cao Y, Wei Y, Wang K*,Huang C*. Regorafenib induces lethal autophagy arrest by stabilizing PSAT1 in glioblastoma. Autophagy. 2020; 16(1):106-22. 106. Chen H-N, Chen Y, Zhou Z-G, Wei Y, Huang C*. A novel role for ketoconazole in hepatocellular carcinoma treatment: linking PTGS2 to mitophagy machinery. Autophagy. 2019; 15(4):733-4. 105. Zhou L, Gao W, Wang K, Huang Z, Zhang L, Zhang Z, Zhou J, Nice EC, Huang C*. Brefeldin A Inhibits Colorectal Cancer Growth by Triggering Bip/Akt-regulated Autophagy. FASEB J. 2019; 33(4):5520-34. 104. Wang K, Jiang J, Lei Y, Zhou S, Wei Y, Huang C*. Targeting Metabolic-redox Circuits for Cancer Therapy. Trends Biochem Sci. 2019; 44(5):401-14.(ESI 高被引论文) 103. Zhang Z, Zhang L, Zhou L, Lei Y, Zhang Y*, Huang C*. Redox signaling and unfolded protein response coordinate cell fate decisions under ER stress. Redox Biol. 2019; 25:101047.(ESI 高被引论文) 102. Chen Y, Chen H-N, Wang K, Zhang L, Huang Z, Liu JY, Zhang Z, Luo MC, Lei YL,Peng Y, Zhou Z-G, Wei YQ, Huang C*. Ketoconazole exacerbates mitophagy to induce apoptosis by downregulating cyclooxygenase-2 in hepatocellular carcinoma. J Hepatol. 2019; 70(1): 66-77. 101. Liu Y, Guo JZ, Liu Y, Wang K, Ding W, Wang H, Liu X, Zhou S, Lu XC, Yang HB, XuC, Gao W, Zhou L, Wang YP, Hu W, Wei Y, Huang C*, Lei QY*. Nuclear Lactate Dehydrogenase A Senses ROS to Produce α-Hydroxybutyrate for HPV-induced Cervical Tumor Growth. Nat Commun. 2018; 9(1):4429. 100. Peng L, Cantor DI, Huang C, Wang K, Baker MS*, Nice EC*. Tissue and plasma proteomics for early stage cancer detection. Mol Omics. 2018; 14(6):405-23. 99. Lan J, Huang Z, Han J, Shao J*, Huang C*. Redox regulation of microRNAs incancer. Cancer Lett. 2018; 418:250-9. 98. Jin P, Lan J, Wang K, Baker MS, Huang C*, Nice EC*. Pathology, proteomics and the pathway to personalised medicine. Expert Rev Proteomics.2018;15(3):231-43. 97. Wang K, Zhang T, Lei Y, Li X, Jiang J, LanJ, Liu Y, Chen H, Gao W, Xie N, Chen Q, Zhu X, Liu X, Xie K, Nice EC, Wu M*,Huang C*, Wei Y. Identification of Annexin A2 as a Specific Bleomycin Target to Induce Pulmonary Fibrosis by Impeding TFEB-mediated Autophagic Flux. Autophagy. 2018; 14(2):269-82. 96. Jiang J, Wang K, Chen Y, Chen H, Nice EC*, Huang C*. Redox regulation in tumor cell epithelial-mesenchymal transition: molecular basis and therapeutic strategy. Signal Transduct Target Ther. 2017; 2:17036. 95. Jin P, Wang K, Huang C*, Nice EC*. Mining the fecal proteome: from biomarkers to personalised medicine. Expert Rev Proteomics. 2017; 14(5):445-59. 94. 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